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Student Applied Mathematics to Improve Liver Imaging Methods

By Petrina Smith
Thursday, 08 May, 2014

Third year medical undergraduate Charles Baker has applied his background in mathematics to the field of nuclear medicine to improve liver imaging methods, which may improve diagnosis time and possibly save patients undergoing unnecessary surgery.
Mr Baker, a University of Queensland student, 聽has developed a mathematical model that can be programmed into existing scanning equipment to enhance images of patients鈥 livers.
Mr Baker said the model uses variables specifically relating to the structure of the liver to help nuclear medicine specialists better differentiate between healthy and damaged liver tissue.
鈥淭his means we can improve the output of existing scanning equipment to provide better image quality for nuclear medicine specialists,鈥 Mr Baker said.聽鈥淭he resulting images demonstrate higher contrast between healthy liver tissue and unhealthy liver tissue, such as malignant tumours.鈥
The mathematical model is undergoing clinical appraisal in the Nuclear Medicine Department at the Royal Brisbane and Women鈥檚 黑料吃瓜群网 (RBWH) and Mr Baker said initial feedback had been encouraging.
鈥淲e hope that practical testing of the model across a larger number of images will help identify how it will improve clinical decision-making and patient outcomes.鈥
鈥淔or example, scans using the mathematical model may help to more clearly identify areas of dead tumour tissue and active tumour tissue. Clinicians can use this information to better target treatments.鈥
The improved contrast would also help specialists to more easily interpret scans, saving time.
鈥淢ost importantly, the higher contrast scans might save people from undergoing unnecessary surgical procedures,鈥 Mr Baker said.
He is now working on mathematical models to improve imaging in other parts of the body, such as the brain.
Mr Baker developed the model under the supervision of Dr Nicholas Dowson and Professor Steven Rose, from The Australian eHealth Research Centre, CSIRO, and Dr Paul Thomas, Associate Director of Specialised PET Services, Department of Nuclear Medicine, RBWH.
Mr Baker was recently recognised for his work with the Undergraduate Prize in Canon Australia鈥檚 Extreme Imaging Competition

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