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Research Aimed at Simplifying Prostate Cancer Test

By Petrina Smith
Monday, 03 November, 2014


University of Queensland researchers are working on a prostate cancer test that is as simple as a pregnancy test.
Dr Matthew Roberts, from UQ鈥檚聽School of Medicine, said he was building on the work of聽UQ Centre for Clinical Research鈥檚 Professor Frank Gardiner in improving prostate cancer diagnosis.
鈥淲e鈥檙e trying to develop a test that will assist or replace the PSA test by looking for markers for the cancer in urine and semen,鈥 Dr Roberts said.
Dr Roberts said the current blood test for prostate cancer 聽could falsely predict the cancer and wasn鈥檛 accurate enough to detect small cancers.
鈥淟ike most cancers, the earlier you find it, the earlier you can treat it,鈥 he said.聽鈥淧rostate cancer is the most commonly diagnosed internal cancer in men, affecting about 20,000 Australians every year.聽鈥淚t鈥檚 also a cancer that, if not detected early, can have a serious impact on a man鈥檚 quality of life.聽鈥淚f deposits get into their bones, the treatment is to suppress testosterone levels, which has side-effects, including heart problems, sexuality and psychologically.
鈥淥ur vision is to design a non-invasive test similar to a pregnancy test that could be used to select those men who are likely to benefit from further investigation in the form of MRI and biopsy procedures.鈥
Professor Gardiner said it was still taking too long to diagnose the cancer and quicker detection would lead to better targeted treatment.
鈥淲e anticipate that when we can pick it up earlier than it is being diagnosed at present then we use it for triaging patients to select those who would then go on to have MRIs and biopsies,鈥 he said.
鈥淲e need to find the earliest changes in these cells using other methods and the logical place to start was by looking at bodily fluids because about 40 per cent of ejaculate comes from the prostate.鈥
Dr Roberts and Professor Gardiner said the research was ongoing and it could be several years before a test was available. His聽research is funded through Cancer Council Queensland

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